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What is CBGA?November 15, 2018
This week, we’re talking about the most pivotal chemical compound found in weed. Cannabigerolic acid, also known as CBGA, is the cannabinoid that makes cannabis sativa unique from other plants.
All plants undergo different chemical processes to break down and create different chemical compounds in the natural course of their life. This process is called biosynthesis. For example, photosynthesis is the process in which green plants and other organisms transform water and carbon dioxide into oxygen and other energy rich chemical compounds with the use of sunlight. Similarly, olivetolic acid and geranyl pyrophosphate, two naturally occurring compounds found in cannabis, are biosynthesized to create CBGA.
The Importance of CBGA
CBGA is the essential cannabinoid in cannabis because all other cannabinoids are formed from it. In 1975, researchers found that CBGA was the first cannabinoid to be formed in the trichomes of a cannabis plant. In other living organisms like humans, there are certain cells called stem cells. Stem cells are the building blocks of the human body. They have the amazing ability to be transformed into other cells through the course of their life cycle. CBGA is often likened to stem cells because all of the cannabinoids we have studied derive from CBGA. At a certain point in the plant’s maturation process, CBGA is diverted in to creating either THCA, CBDA, or CBCA. Then, through another process, these compounds become THC, CBD, and CBC. Additionally, other cannabinoids are formed in later biosyntheses that these compounds go through, like CBN, which is a compound that comes from THC when it is exposed to light and air.
Medical Benefits of CBGA
While most of the research on CBGA has been around its stem cell-like properties, one study revealed that CBGA may be effective in mitigating apoptosis, otherwise known as programmed cell death, which means it could be powerful in fighting certain kinds of cancer.
More research needs to be done to reveal the other potential properties of CBGA.
Possible Risks of CBG
There is not enough research at this time to accurately assess the potential risks associated with CBGA. As always, if you are concerned, you should seek advice from a trusted medical professional.
The Entourage Effect and Total Plant Medicine
Research suggests that the use of pure extracts of any cannabinoid or terpene is not as effective as when they are paired with other cannabinoids and terpenes. These compounds have a synergistic effect, working in tandem to interact with your body’s endocannabinoid system. Studies have shown that consistent use, as well as the use of a variety of cannabinoids at different potencies, shows better results in the treatment of various symptoms.
Think of it like taking a multivitamin, the increased and consistent levels of vitamins in your immune system promote the overall efficiency of your immune system and will show improvement over time. Similarly, research suggests that consistency of use of cannabinoids promotes the overall effectiveness of the endocannabinoid system.
Disclaimer: Keep out of reach of children. For use only by adults 21 years of age and older.